PureBulk

Supplement Facts Volumetrics Certificate of Analysis

CAUTION: This product is potentially toxic in very small amounts. This concentrated product is not intended for general use. It should only be used by professionals with the necessary skills to accurately measure very small quantities. Do not purchase this product unless you are a compounding pharmacist or other health care professional. We request that you contact us via email at store@purebulk.com prior to pre-qualify your purchase. If you do not have the analytical skills necessary to measure it safely, you should not order this product.

Related Products: If you are not a compounding pharmacist or other health care professional, you may be interested in Vitamin D3 capsules.

What is Vitamin D3 (cholecalciferol)?

Vitamin D3, otherwise known as cholecalciferol, is a pro-hormone and essential nutrient produced in the skin. It is a seco-steroid hormone that regulates calcium homeostasis and balance within the body.

Vitamin D is best known for its role in the development and maintenance of healthy teeth, bones and cartilage. Vitamin D helps the body keep bones and teeth strong by improving the absorption of calcium and phosphorus from the small intestine. Vitamin D also affects parathyroid hormone, which regulates bone turnover and release of calcium from bone.

There are two sources, vitamins D2 and D3. Vitamin D2, ergocalciferol, is considered a poor choice and is derived from sources such as fortified milk, herring, mackerel, tuna, salmon, sardines, eggs, fortified cereals and baked goods.

Vitamin D3, cholecalciferol, is the more active and preferable form of vitamin D. It is the most widely known of the vitamin D series. Vitamin D3 is preferred because it has a higher bioavailability and it has more roles in biological activity for its various metabolites or isomers that have biological benefit.

Vitamin D is known as the "sunshine vitamin" because it can be produced photochemically by the action of sunlight or ultraviolet light from the precursor sterol 7-dehydrocholesterol, which is present in the skin. Vitamin D formed in this manner is called "natural vitamin D" or vitamin D3. Sun exposure for just 15 minutes daily can provide 2,000 to 5,000 IU of vitamin D.

Vitamin D3 can also be obtained from animal products (such as eggs or fish) and fortified foods or can be consumed in the form of fish oil. As a fat-soluble vitamin, it is stored to a certain extent in the body.

Health Benefits of Vitamin D3 (cholecalciferol)

Vitamin D deficiency can lead to serious effects. Children without adequate vitamin D are more susceptible to developing rickets, a disease characterized by deformation of bones and teeth. Adults with insufficient amounts of vitamin D have an increased risk of developing osteomalacia (similar to rickets), and are more likely to suffer from osteoporosis, a bone-weakening disease.

The primary function of vitamin D is to promote and enhance calcium and magnesium absorption, the two essential minerals necessary for strong bones. Vitamin D3 is also required for the body to be able to utilize phosphorus, and for the absorption and metabolism of vitamin A.

By increasing GI absorption of phosphorus and calcium, cholecalciferol increases serum calcium concentrations, which in turn increases osteoclastic resorption and distal renal tubular reabsorption of calcium, whose optimal levels are required to ensure proper bone mineral density and serum (blood) calcium levels.

This is extremely beneficial among very young children where it can treat rickets in conjunction with vitamin A, and in the treatment of osteoporosis in the elderly, especially post menopausal women who often suffer from fractures due to loss of bone density.

Purity and Concentration of Vitamin D3 (cholecalciferol)

This PureBulk Vitamin D3 (cholecalciferol) powder has a concentration of 100,000 IU/gram and contains no fillers, taste additives or anti-caking agents.

IU refers to International Units, a standard of measurement regarding the amount of the vitamin.

Suggested Use of Vitamin D3 (cholecalciferol)

Prior to purchasing this product, we request that you contact us via email at store@purebulk.com to let us know why you are qualified to purchase, handle and measure this product safely.

If you are not a compounding pharmacist or health professional, buy our Vitamin D3 capsules instead.

As a dietary supplement, take 10 mg to 50 mg daily (or as directed by physician). Use ONLY an accurate milligram scale to measure!

The U.S. Food and Drug Administration (FDA) recommends a Daily Value (DV) of 400 IU for adults and children four or more years of age. A serving of just 4 milligrams (mg) of Purebulk's Vitamin D 100,000 IU/g will provide 100 % of the Daily Value. A serving size of 10 milligrams(mg) will provide 1000 IU or 250% of the Daily Value(DV). A serving size of 50 mg will provide 5000 IU or 1250% of the DV.

At 100,000 IU per gram, the suggested serving size is extremely small! Because Vitamin D3 can potentially be TOXIC if taken in excess, extreme care should be exercised when measuring this product. DO NOT ATTEMPT TO MEASURE THIS PRODUCT USING MEASURING SPOONS OF ANY KIND! The only safe way to measure this product for individual use will be using an accurate milligram weight scale. PureBulk offers these scales, and you can purchase one quite inexpensively here: 1/100th gram (milligram) weight scales.

Potential Side Effects of Vitamin D3 (cholecalciferol)

Like other fat-soluble vitamins, vitamin D can be TOXIC. Vitamin D supplements should be taken with caution!

Excess amounts can be stored in body tissue and may lead to hypercalcemia and excess bone loss. Individuals at particular risk include those with hyperparathyroidism, kidney disease, sarcoidosis, tuberculosis, or histoplasmosis.

Symptoms of too much vitamin D include nausea, weakness, constipation, irregular heartbeat, weight loss, seizures and irritability.

Solubility and Suggested Preparation of Vitamin D3 (cholecalciferol)

Vitamin D3 is fat soluble or not soluble in water. It is best to take this product at meal times with fatty foods.

How should I store it?

You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

References & Further Research

University of Maryland Medical Center: Vitamin D

Linus Pauling Institute: Vitamin D

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.