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Thiamine Mononitrate (Vit B1)

What is Thiamine HCl (Vitamin B1)?

Thiamine HCl (vitamin B1) is essential in the body's use of carbohydrates as an energy source and for metabolizing amino acids. Thiamine requirements are increased when the body relies heavily on carbohydrates as a main source of energy.

Thiamine is also needed to process fats and proteins. Every cell of the body including nerve cells requires vitamin B1 to form adenosine triphosphate (ATP), the fuel the body runs on.

Thiamine is an essential nutrient and vitamin that promotes normal metabolic function and processes in human physiology. Vitamin B1 keeps the heart muscles healthy and is critical to the maintenance of a well-functioning brain and nervous system.

Vitamin B1 is a crystalline, yellow-white, water-soluble compound that is heat and alkali reactive when placed in solution. Since it is readily expelled from the body it must be consumed regularly for optimal nutritional benefit.

Vitamin B1 (Thiamine) is available from both natural and synthetic sources. Natural sources include baked potatoes, raisins, beef kidneys, flour, whole grains, beans, wheat germ, sunflower seeds, nuts, oranges, asparagus, cauliflower, milk, whole wheat bread, oatmeal and brown rice. It is found in salmon steak, pork, beef and chicken and fortified breads and cereals.

Thiamine is mainly the transport form of the vitamin, while the active forms are phosphorylated thiamine derivatives. There are five known natural thiamine phosphate derivatives: thiamine monophosphate (ThMP), thiamine diphosphate (ThDP), also sometimes called thiamine pyrophosphate (TPP), thiamine triphosphate (ThTP), and the recently discovered adenosine thiamine triphosphate (AThTP) and adenosine thiamine diphosphate (AThDP).

Thiamine helps the body make thiamine pyrophosphate (TPP), which plays an essential role as a cofactor in carbohydrate metabolism (converting food into energy) and in the metabolism of many essential amino acids, including the branched chain amino acids (essential amino acids L-Leucine, L-Isoleucine, and L-Valine).

Thiamine's principle analog is thiamine diphosphate (TDP), found almost exclusively in circulating red blood cells. TDP is a necessary cofactor for many enzymes, including transketolase and pyruvate dehydrogenase.

Vitamin B1 assists in blood formation, enhances circulation and optimizes cognitive activity and brain function. It has a positive effect on energy, growth, normal appetite and learning capacity and is needed for muscle tone of the intestines, stomach, and heart.

The highest concentrations of vitamin B1 are found in muscle, heart, liver, kidneys and brain. Vitamin B1 is not only the first of the B vitamins discovered but is also one of the first substances to be identified as a vitamin. As with other B vitamins, vitamin B1 should be consumed on a daily basis as it is not stored by the body.

Health Benefits of Thiamine (Vitamin B1)

Thiamine (Vitamin B1) is necessary for the body to properly metabolize and process carbohydrates, fat and protein and is critical for the healthy metabolic function of mitochondrial ATP synthesis, the most basic unit of energy that fuels every cell in the human body. Without enough vitamin B1, the body can not transform this sugar into usable energy.

Vitamin B1 is necessary for proper blood formation, the production of hydrochloric acid and proper digestive function. Vitamin B1 (thiamine) supplementation can also benefit energy, growth, normalized appetite, learning, cognitive function and smooth muscle tone of the intestines, stomach and heart.

Vitamin B1 can also act as an antioxidant protecting the body against the effect of free radical molecules, which can damage cell membranes.

Purity and Concentration of Thiamine (Vitamin B1)

This thiamine HCl powder does not contain any fillers, additives or anti-caking agents.

Suggested Use of Thiamine (Vitamin B1)

The suggested serving size for thiamine is 125 milligrams daily, or as directed by a physician. You can see the full bulk density/volumetric conversion chart for thiamine here. A serving size of 1/16 teaspoon is equal to 126 milligrams (mg)

The U.S. Food and Drug Administration (FDA) recommends a Daily Value (DV) of 1.5 milligrams (mg) of thiamine for adults and children four or more years of age. Thiamin HCl yields 89% actual thiamine (the rest being the hydrochloride). A serving of 126 mg (1/16 tsp) will provide 112 milligrams of thiamine, 7400% of the Daily Value.

Potential Side Effects of Thiamine (Vitamin B1)

Because thiamine is water soluble, it is unlikely to reach toxic levels. Like most of the B vitamins, deficiency is a much greater concern. Thiamine deficiency, also called beriberi, occurs as a result of many factors, including crash dieting, alcohol abuse, liver dysfunction and other medical problems. Also at risk are those who consume a lot of sweets, soft drinks and highly processed foods.

A lack of sufficient thiamine in the diet can cause loss of appetite, poor digestion, chronic constipation, loss of weight, mental depression, nervous exhaustion and insomnia. It can lead to muscular weakness, leg cramps, slow heartbeat, irritability, defective hydrochloric acid production in the stomach and consequent digestive disorders.

Bioavailability, Mixing & Solubility of Thiamine HCl(Vit B1)

Thiamine HCl powder dissolves quickly in warm or hot water, but rather slowly in cold water. Mix with water or juice and drink.

In order to gain the maximum benefits of vitamin B1 it is advisable to incorporate it into the daily diet and to take it with other B vitamins such as vitamin B2 and B6 (riboflavin and pyridoxine respectively) as part of a complete formula. Vitamin B1 and B6 become more effective when they are given the chance to work synergistically together.

Absorption of thiamine is entirely dependent upon getting enough vitamin B6, vitamin B12, and folic acid.

Those who drink a lot of coffee or tea may benefit from supplementation, as drinks containing caffeine act as a diuretic. Those beverages cause both water and water-soluble vitamins (such as thiamine) to be eliminated from the body more quickly.

How should I store it?

You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

References & Further Research

Linus Pauling Institute, Micronutrient Information Center: Thiamine


University of Maryland Medical Center: Vitamin B1 (thiamine)

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.