PureBulk

Supplement Facts Volumetrics Certificate of Analysis

Related Products: L-Valine gelatin capsules 450mg, L-valine vegetarian capsules 450mg.

What is L-Valine?

L-valine is an essential amino acid required for the smooth functioning of the nervous system and to aid muscular development in the body.

It is one of the three Branched-Chain Amino Acids (BCAAs). The other two are L-leucine and L-isoleucine.

"Branched chain" refers to a chemical structure setting BCAAs apart from other amino acids. Up to 25% of total protein dietary intake are BCAAs, used by the body to promote the healing of injured tissues and to protect against muscle tissue breakdown (catabolism) during exercise.

BCAAs are the single most important group of amino acids for just about anyone, from world champion athletes to regular people. BCAAs comprise one-third of all the protein in muscles.

L-valine specifically helps maintain nitrogen balance in the body, essential for muscular development.

L-valine is an essential amino acid because it cannot be manufactured by the body and must be obtained through food or dietary supplements.

L-valine and the other BCAAs are not processed in the liver. They are metabolized in the muscle, directly and significantly influencing muscle-protein metabolism and aiding recovery after intense exercise.

The production of glucose for energy during intense physical activity is supported by L-valine, reducing muscle breakdown.

L-valine also influences the brain's uptake of neurotransmitter precursors tryptophan, phenylalanine, and tryosine.

Valine helps eliminate potentially toxic excess nitrogen from the liver and transports nitrogen to other parts of the body where it is needed.

Athletes who train or exercise frequently or have a low-protein diet should consider valine supplementation. Although it is available in stand-alone supplemental form, it should always be taken together with the other two branched-chain amino acids, isoleucine and leucine.

The correct balance is 2:1:1: two parts L-leucine and for every one part of L-valine and L-isoleucine.

Studies have shown BCAA to be helpful in other areas due to what each amino acid does in its own right. For example, leucine is necessary for wound recovery to skin and bones and helps protect muscles, valine helps promote or maintain nitrogen balance (essential for muscular development), and isoleucine helps boost energy and is necessary for forming hemoglobin.

Some natural sources and food products that contain L-valine include meat, leafy vegetables, mushrooms, peanuts, soy protein, kidney beans, poultry and milk.

Health Benefits of L-Valine

L-valine is needed for muscle metabolism, tissue repair and the maintenance of a proper nitrogen balance in the body. It can be used as an energy source by muscles.

L-Valine is typically taken (with the other BCAAs) by weightlifters and performance athletes. Blood levels of L-valine will fall significantly after strenuous exercise and will stay low until complete recovery occurs. Supplementation with L-valine one hour before strenuous workouts can reduce the recovery time by increasing muscle protein synthesis and counteracting catabolic processes.

Purity and Concentration of L-Valine

This pharmaceutical-grade amino acid contains no fillers, taste additives or anti-caking agents.

Suggested Use of L-Valine

The suggested serving size for L-valine is 1000 to 2000 milligrams taken once or twice a day, together with the same amount of L-isoleucine and twice as much L-leucine. Some athletes use larger amounts based on individual preference or the recommendation of a professional trainer.

You can see the full bulk density/volumetric conversion chart for L-valine here. A serving size of 1/2 teaspoon is equal to 1650 milligrams.

PureBulk also sells the three branched-chain amino acids (BCAAs) as a blended powder product and in a blended capsule form.

Potential Side Effects of L-Valine

L-valine is safe at suggested serving sizes. Too much valine in the diet can disrupt liver and kidney function by increasing the amount of ammonia in the body. People with impaired liver or kidney function should not take isoleucine without first consulting a physician. It is not recommended for women who are pregnant or nursing.

Bioavailability, Mixing and Solubility of L-Valine

L-Valine powder is not easily soluble in water and has a bitter taste. The best way to take L-valine powder is blended within a protein shake.

How should I store it?

You will receive this powder in a resealable bag. Store it in a cool, dry, dark location. Reseal tightly between uses.

References & Further Research

Wikipedia: Branched-chain amino acids

Influence of ingesting a solution of branched-chain amino acids on plasma and muscle concentrations of amino acids during prolonged submaximal exercise.

Branched-chain amino acids augment ammonia metabolism while attenuating protein breakdown during exercise

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.