PureBulk

Supplement Facts Volumetrics Certificate of Analysis

What is L-Leucine?

L-leucine is an amino acid obtained through the hydrolysis of protein by pancreatic enzymes during digestion. It is necessary for optimal growth in infants and children and for the maintenance of nitrogen balance in adults.

Along with isoleucine and valine, it is one of the three essential branched-chain amino acids (BCAAs) that make up a significant portion of the total amino acid count in the body's protein structure.

Leucine aids the body's production of energy. Athletes engaged in strenuous activity require high amounts of this nutrient.

The ideal balance of the BCAAs is two parts L-leucine for every one part of L-valine and one part of L-isoleucine.

Good natural sources of leucine include brown rice and beans, all types of meats and poultry, cheese, nuts, whole wheat and soy flour.

One of the main functions of leucine is in regulating protein metabolism in the body. The availability of leucine is of critical importance in controlling the net synthesis of protein.

L-leucine is widely used as an ingredient in supplements for muscle building because of its many beneficial effects on sports performance. It helps preserve lean muscle tissue, supplies the body with energy under stress and keeps muscle glycogen (glucose stored in muscle tissue used to power muscular contraction) and nitrogen balance in check.

The BCAAs are the most important group of amino acids for just about anyone. They work together inside the body to protect muscle and act as fuel in the biochemistry of the body. They promote healing of injured tissues, speed up recovery and protect against muscle tissue breakdown (catabolism) during exercise.

Health Benefits of L-Leucine

Leucine functions best with isoleucine and valine in repairing muscles, acting in regulating blood sugar and providing the body with energy. It also improves and stimulates production of growth hormones and helps burn visceral fat, adipose tissue located in the deepest layers of the body which are least responsive to dieting and exercise.

Because of this, L-leucine is typically taken by weightlifters and performance athletes working to reduce fat and maximize muscle mass.

In preventing muscle loss, leucine is the most effective of the BCAAs because it is converted to glucose more quickly than isoleucine and valine.

Blood levels of L-leucine will significantly decrease after strenuous exercise and will stay low until recovery is complete. Supplementation with L-leucine one hour before strenuous workouts can shorten the recovery time considerably by increasing muscle protein synthesis and counteracting catabolic processes.

Purity and Concentration of L-Leucine

This pharmaceutical grade amino acid contains no fillers, taste additives or anti-caking agents.

Potential Side Effects of L-Leucine

Leucine is considered safe at suggested serving sizes. Those with impaired liver or kidney function should not take leucine without first consulting a physician, as large doses of amino acids may aggravate these conditions. This product is not recommended for women who are pregnant or nursing.

Suggested serving size of L-Leucine

As a dietary supplement, take 2.5 grams (1/2 tablespoon) twice a day, or as directed by physician. Individual needs vary. You can see the full bulk density/volumetric conversion chart for L-Leucine here. One level half-tablespoon of L-leucine will be equivalent to about 2452 milligrams or about 2.5 grams. One level half-tablespoon taken twice per day about one hour before workouts will yield a total daily dose of 5 grams.

Again, keep in mind that to get the most out of supplementing with L-leucine it should be taken at a ratio of two parts L-leucine for every one part of L-valine and for every one part of L-isoleucine.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Bioavailability, Mixing and Solubility of L-Leucine

PureBulk L-leucine powder is not easily soluble in water and has a bitter taste. The best way to take L-leucine powder is mixed within a protein shake.

How should I store it?

You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.

References & Further Research

Wikipedia: Amino Acids