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What is DL-Phenylalanine (DLPA)?

Phenylalanine is an essential amino acid that is necessary for the normal functioning of the central nervous system.

DL-phenylalanine (DLPA) is a 50/50 mixture of the synthetic D- form made in a laboratory and the L- natural form of this amino acid found in proteins. Phenylalanine is one of the few amino acids that can be utilized in its D- form.

Because DL-phenylalanine (DLPA) contains 50% L-phenylalanine and 50% D-phenylalanine, it possesses some of the effects of both forms.

Health Benefits of DL-Phenylalanine (DLPA)

DL-phenylalanine is a dietary supplement that aids in pain management and proper mood balance.

Phenylalanine plays a role in mood, appetite and mental alertness. It functions and acts as a building block for numerous proteins that are produced in the body.

The pain relieving effects of D-phenylalanine are believed to occur from its enhancing levels of endorphins and enkephalins, the body's naturally occurring opiates.

Phenylalanine occurs as a constituent of many proteins and is normally converted to tyrosine in the body.

Tyrosine is an amino acid that aids in making proteins, certain brain chemicals and thyroid hormones. Tyrosine helps produce the neurotransmitters dopamine, epinephrine and norepinephrine. These compounds transmit signals between nerve cells.

In the liver, phenylalanine is involved in many biochemical reactions, like protein synthesis and oxidative catabolic reactions.

Purity and Concentration of DL-Phenylalanine (DLPA)

DL-Phenylalanine (DLPA) powder contains no fillers, taste additives or anti-caking agents.

Suggested Use of DL-Phenylalanine (DLPA)

The suggested serving size for DL-phenylalanine (DLPA) is 375 milligrams (1/4 teaspoon) taken three or four times daily, or as directed by a physician. Individual needs vary.

Before its maximum effects become apparent it is usually necessary to take DLPA for two to four weeks.

You can see the full bulk density/volumetric conversion chart for DL-Phenylalanine (DLPA) here.

Potential Side Effects of DL-Phenylalanine (DLPA)

WARNING: DO NOT USE with prescription antidepressants. Those with phenylketonuria should not take this product. PKU is a rare metabolic disorder that occurs in people who are missing an enzyme that is needed to properly metabolize phenylalanine.

DO NOT use phenylalanine supplements together with prescription antidepressants, especially monoamine oxidase (MAO) inhibitors, as this may lead to life-threatening spikes in blood pressure.

Excessive use of DL-phenylalanine may lead to headaches, nausea and heartburn, increased blood pressure and emotional agitation, insomnia, headaches, and tyrosine toxicity. Nerve damage may occur. Those with high blood pressure or migraines should not take phenylalanine or even eat foods high in this amino acid, as it may aggravate their condition. This product is not recommended for women who are pregnant or nursing. People with melanoma should avoid phenylalanine supplementation.

Bioavailability, Mixing and Solubility of DL-Phenylalanine (DLPA)

This product dissolves somewhat slowly in cold water, but faster in hot water, and has very little flavor or taste. Mix with water or juice and drink.

References & Further Research

University of Maryland Medical Center: Phenylalanine

Wikipedia: Phenylalanine

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.