PureBulk

Supplement Facts Volumetrics Certificate of Analysis

Related PureBulk products:

D-glucosamine-hcl-shellfish, D-glucosamine-hcl-vegan, D-glucosamine-sulfate-k-gelatin and vegetarian capsules.

What is D-Glucosamine Sulfate Potassium?

Glucosamine, an amino derivative of the simple sugar glucose, is an important constituent of many natural polysaccharides and supports cartilage. Glucosamine is a naturally occurring chemical found in the body. This product combines the amino acid polymer with potassium and sulfate (SO4).

Glucosamine helps the body synthesize and produce specialized molecules called glycosaminoglycans. Glucosamine plays an important role as an intermediate in the biosynthetic pathway of proteoglycans, the main building blocks of connective tissue and cartilage.

Glucosamine is available in different forms, including glucosamine hydrochloride, glucosamine hydroiodide, glucosamine sulfate and N-acetyl glucosamine. Glucosamine sulphate is the most preferred form of glucosamine.

Glucosamine is often taken with chondroitin. Both are basic constituents of articular cartilage. They are often taken together with manganese, a trace metal needed for building cartilage. Glucosamine is sometimes combined with methylsulfonylmethane in nutritional supplements.

Difference between the other Glucosamine salts

There have been discussions over which of the two glucosamine salts, hydrochloride or sulfate, is preferred. Both salts, in the pure form, deliver equally effective amounts of glucosamine to joint cartilage. If there is a preference, it is usually based on relative purity and economics. Purebulk also offers D-Glucosamine Hydrochloride powder from both vegan and shellfish sources.

Benefits of D-Glucosamine-HCL

Glucosamine helps replenish synovial fluids. It is easily absorbed into the bloodstream and is important in the formation and development of skin, eyes, bones, tendons, nails, ligaments, and parts of the heart.

Glucosamine supplies the primary substrate for both collagen and proteoglycan synthesis. Glucosamine triggers the synthesis and production of glycosaminoglycans and proteoglycans, two crucial building blocks of cartilage. The polysaccharide groups in proteoglycans are known as glycosaminoglycans or GAGs. GAGs include hyaluronic acid, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparin and heparan sulfate. All of the GAGs contain abundant derivatives of glucosamine or galactosamine. Glucosamine also triggers the integration of sulfur into cartilage.

Glucosamine is needed in the production of mucous as a protective coating in the urinary, digestive, and respiratory tracts. Sufficient levels of glucosamine in the blood are necessary for the production of hyaluronic acid, which helps the body heal skin injuries.

Purity and Concentration of D-Glucosamine-Sulfate-Potassium

This food grade D-glucosamine sulfate potassium is harvested from shrimp and crab shells and contains no fillers, taste additives, or anti-caking agents.

Potential Side Effects of D-Glucosamine Sulfate Potassium

Persons with allergies to shellfish should avoid this product. There is no evidence that those sensitive to sulfites or sulfa drugs are at any risk. Glucosamine sulfate can cause mild side effects including nausea, heartburn, diarrhea, and constipation. Uncommon side effects include drowsiness, skin reactions and headache. Pregnant women and breast-feeding mothers should not take glucosamine sulfate. People with asthma should be cautious about taking products containing glucosamine. Recent studies indicate that glucosamine sulfate does not seem to affect the blood sugar level in people with type 2 diabetes though sugar levels should be closely monitored.

Bioavailability, Mixing and Solubility of D-Glucosamine Sulfate Potassium

D-glucosamine sulfate potassium is an odorless white crystalline powder with a mild, sweet taste. It is freely soluble in water or juice, slightly soluble in methanol and insoluble in ethanol. It dissolves (ionizes) completely in the stomach's hydrochloric acid and is readily available for absorption in the small intestine. Once absorbed into the bloodstream, glucosamine, independent of the original salt, is available to the body.

Suggested Use of D-Glucosamine-Sulfate-Potassium

The suggested serving size for D-glucosamine sulfate potassium is 1000 milligrams taken up to three times daily, depending on individual needs. As you can see from the volumetric measuring chart a serving size of 1/4 teaspoon is about equal to 1000 mg (1 gram).

References and Further Research on D-Glucosamine-HCL

University of Maryland Medical Center: Glucosamine

National Center for Complementary and Alternative Medicine: Questions and Answers: NIH Glucosamine/chondroitin Arthritis Intervention Trial Primary Study

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.